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Merck Nasivion Nasal Spray 10 ml

Product SKUId: 08ENT0000003

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10 ml Spray
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About Product
  • Company Name/Manufacturer:
    Merck Ltd
  • Brand Name:
    MERCK LTD
  • Description:
    • It contains Oxymetazoline Topical (0.05% w/v). Oxymetazoline important in Nasal drops or spray. Some precaution need to take before the medication of this product like during Pregnancy, lactation. Difficulty in urination secondary to prostate enlargement. Oxymetazoline is a sympathomimetic that selectively agonizes a1 and, partially, a2 adrenergic receptors. Since vascular beds widely express a1 receptors, the action of oxymetazoline results in vasoconstriction. In addition, the local application of the drug also results in vasoconstriction due to its action on endothelial postsynaptic a2 receptors, systemic application of a2 agonists, in contrast, causes vasodilation because of centrally-mediated inhibition of sympathetic tone via presynaptic a2 receptors.Vasoconstriction of vessels results in relief of nasal congestion in two ways: first, it increases the diameter of the airway lumen; second, it reduces fluid exudation from postcapillary venules.It can reduce nasal airway resistance (NAR) up to 35.7% and nasal mucosal blood flow up to 50%. Oxymetazoline is available over-the-counter as a topical decongestant in the form of oxymetazoline hydrochloride in nasal sprays.

  • Contra-Indications

    Avoid during Pregnancy, lactation, Glaucoma, hyperthyroidism, heart disease (including angina), hypertension, advanced arteriosclerotic conditions, Children <6 yr.

  • Usage

    Relief from blocked nose, Nasal congestion

  • Side Effects

    Prolong use may cause Burning, sneezing, dryness of mouth and throat, rebound congestion, Headache, insomnia, tachycardia, hypertension, nervousness, nausea, dizziness, palpitation, arrhythmia.

  • Ingredients

    Oxymetazoline Topical (0.05% w/v)

  • Dosage

    Spray 1-3 doses into each nostril twice daily.